Health (Human & Animal)

The FAO GM Foods Platform is a simple online platform to share information on safety assessment of foods derived from recombinant-DNA plants authorised in accordance with the Codex “Guideline for the conduct of food safety assessment of foods derived from recombinant-DNA plants (CAC/GL 45-2003, annex III adopted in 2008) ". This Platform also facilitates the effective utilisation of food safety assessment in situations of Low Level Presence (LLP) of r-DNA plant materials in food.
Information Platform for Animal health and GM Feed (IPAFEED) is an open-access database, developed as part of EUFP7 “Monitoring of Animals for Feed-related Risks in the Long Term” (MARLON) project, that consists of three sections: 1) “GM feed consumption" contains single measurements of growth, health and productivity parameters of livestock animals fed with GMO-containing feeds made during controlled feeding studies; 2) “DNA and protein detection” contains the results from experiments to detect transgenic DNA fragments or newly expressed proteins in livestock tissues and fluids; and 3) “Health monitoring programs” collected in the course of the MARLON project.
The International Life Sciences Institute (ILSI), Washington DC, USA has developed a publicly-accessible database of crop composition data by compiling their existing analytical data. Their crop composition database contains data for assessing the compositional equivalence of new crop varieties, as well as documenting the broad natural variability in the composition of conventional crops. The database has 70,000 data points on 102 nutritionally important analytes (e.g. amino acids, carbohydrates, fatty acids, fibre, minerals, vitamins, etc.) for maize, cottonseed and soya bean samples obtained from controlled field trials in multiple worldwide locations. The database is searchable on a number of attributes including analyte, matrix, year of harvest, and field location.
The Food Allergy Research and Resource Program (FARRP) Protein Allergen Database at the University of Nebraska, USA contains a list of publicly known allergens. Each entry is identified by the source organism, protein name, allergen designation (if available) and is linked (through a Gene Identifier number) to an accession in Entrez at NCBI. FARRP allows users to compare a sequence to an allergen database on-line (using the FastA program). The database contains a comprehensive list of unique proteins of known and putative allergens (food, environmental and contact) and gliadins that may cause celiac disease. Some entries are from published studies demonstrating clear clinical cause and effect for some individuals with a history of allergy to the source material, whilst others are where the authors of an abbreviated note or a sequence database entry claim that protein is an allergen or binds IgE without published proof. However, proteins that are merely similar in sequence to an allergen (homologues) are not included in the database.
Allermatch™ is a unique website where you can compare the amino acid sequence of a protein of interest with sequences of allergenic proteins. This website carries out automatically the procedures for predicting the potential allergenicity of proteins by bioinformatics approaches as recommended by the Codex alimentarius and FAO/WHO Expert consultation on allergenicity of foods derived through modern biotechnology. The unique features of the Allermatchtm website allow the user in a user-friendly and time-saving manner to enter the input sequence and retrieve, with a few mouse-clicks, the outcomes of interest in an accurate, concise, and comprehensible format
The Structural Database of Allergenic Proteins (SDAP) is a Web server that integrates a database of allergenic proteins with various computational tools that can assist structural biology studies related to allergens. SDAP is an important tool in the investigation of the cross-reactivity between known allergens, in testing the FAO/WHO allergenicity rules for new proteins, and in predicting the IgE-binding potential of genetically modified food proteins. Using this Internet service through a browser, it is possible to retrieve information related to an allergen from the most common protein sequence and structure databases (SwissProt, PIR, NCBI, PDB), to find sequence and structural neighbours for an allergen, and to search for the presence of an epitope other the whole collection of allergens.
The Comprehensive Food Consumption Database is a source of information on food consumption across the European Union (EU). It contains detailed data for a number of EU countries. The database plays a key role in the evaluation of the risks related to possible hazards in food in the EU and allows estimates of consumers’ exposure to such hazards, a fundamental step in EFSA’s risk assessment work.
The USDA Nutrient database provides standard references for the nutrient requirements of humans and domestic animals, including key nutrients, anti-nutrients, and natural toxicants of major food and feeds. Find nutrient information on over 8,000 foods using this new and improved search feature.
Use the SA Food Composition database to find the energy and selected macronutrient (fat, protein, carbohydrate, fibre) composition of different foods.
There are numerous databases that address general toxicological issues (e.g. U.S. National Library of Medicine), and the “Bad Bug Book”). Although they were not initially created to reflect potential toxicity resulting from a genetic modification, they are particularly relevant to food safety.